Environmental determinants of different blood lead levels in children: a quantile analysis from a nationwide survey.
نویسندگان
چکیده
Blood lead levels (BLLs) have substantially decreased in recent decades in children in France. However, further reducing exposure is a public health goal because there is no clear toxicological threshold. The identification of the environmental determinants of BLLs as well as risk factors associated with high BLLs is important to update prevention strategies. We aimed to estimate the contribution of environmental sources of lead to different BLLs in children in France. We enrolled 484 children aged from 6months to 6years, in a nationwide cross-sectional survey in 2008-2009. We measured lead concentrations in blood and environmental samples (water, soils, household settled dusts, paints, cosmetics and traditional cookware). We performed two models: a multivariate generalized additive model on the geometric mean (GM), and a quantile regression model on the 10th, 25th, 50th, 75th and 90th quantile of BLLs. The GM of BLLs was 13.8μg/L (=1.38μg/dL) (95% confidence intervals (CI): 12.7-14.9) and the 90th quantile was 25.7μg/L (CI: 24.2-29.5). Household and common area dust, tap water, interior paint, ceramic cookware, traditional cosmetics, playground soil and dust, and environmental tobacco smoke were associated with the GM of BLLs. Household dust and tap water made the largest contributions to both the GM and the 90th quantile of BLLs. The concentration of lead in dust was positively correlated with all quantiles of BLLs even at low concentrations. Lead concentrations in tap water above 5μg/L were also positively correlated with the GM, 75th and 90th quantiles of BLLs in children drinking tap water. Preventative actions must target household settled dust and tap water to reduce the BLLs of children in France. The use of traditional cosmetics should be avoided whereas ceramic cookware should be limited to decorative purposes.
منابع مشابه
Analysis of Economic Determinants of Fertility in Iran: A Multilevel Approach
Background During the last three decades, the Total Fertility Rate (TFR) in Iran has fallen considerably; from 6.5 per woman in 1983 to 1.89 in 2010. This paper analyzes the extent to which economic determinants at the micro and macro levels are associated with the number of children in Iranian households. Methods Household data from the 2010 Household Expenditure and Income Survey (HEIS) is ...
متن کاملExclusive breastfeeding in the first 6 months of life and its socio-demographic determinants in a nationwide survey in Iran
Introduction: Exclusive breastfeeding for up to 6 months has an important role in infant and maternal health and prevention of child mortality. And the present study aimed to examine the factors affecting exclusive breastfeeding in children under 6 months and evaluate the achievement of the World Health Organization's goal for 2025 at the national level. Materials and Methods: In this national ...
متن کاملEvaluation of Blood Lead Levels in Iranian Children: A Systematic Review
Background and Objectives: Exposure to lead and its effects on children's health is one of the most important and widespread concerns of human societies today. Therefore, the purpose of this systematic study was to evaluate blood lead levels in Iranian children. Materials and Methods: In this systematic review, PubMed, Scopus, Science Direct, Scientific Information Database (SID), and Iran Med...
متن کاملAssociation of Exposure to Fine Particulate Matter and Risk Factors of Non-Communicable Diseases in Children and Adolescents
Background: Risk factors of non-communicable disease (NCD) origin from early life, and exposure to environmental pollutant may be a predisposing factor. This study aimed to investigate the association of air quality index (AQI) and fine particulate matter (PM2.5) with some NCD risk factors in a sample of Iranian children and adolescents. Materials and Methods: This cross-sectional study was con...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Environment international
دوره 74 شماره
صفحات -
تاریخ انتشار 2015